Pioneering Therapeutics for Genetic Pancreatitis

Arwin Health is developing Fc-SPINK1, a first-in-class biologic designed to address the root cause of hereditary and genetic forms of pancreatitis.

Fc Domain
SPINK1
Linker

Transforming Patient Outcomes

We're a dedicated team of scientists and researchers committed to developing breakthrough therapies for patients with unmet medical needs.

First-in-Class

Fc-SPINK1 represents a novel therapeutic approach, targeting the underlying genetic cause of pancreatitis with precision.

Rigorous Science

Our research is grounded in deep understanding of pancreatic biology and guided by the highest standards of scientific rigor.

Patient-Centric

Every decision we make is driven by our commitment to improving the lives of patients affected by genetic pancreatitis.

The Science Behind Fc-SPINK1

A novel approach to treating genetic pancreatitis by restoring the natural protective mechanisms of the pancreas.

Addressing an Unmet Need

Genetic pancreatitis, caused by mutations in genes like PRSS1, SPINK1, and CTRC, affects thousands of patients worldwide with no disease-modifying therapies currently available.

Our lead candidate, Fc-SPINK1, is an Fc-fusion protein designed to:

  • Restore trypsin inhibition in patients with SPINK1 deficiency
  • Provide long-lasting therapeutic effect through Fc-mediated half-life extension
  • Reduce pancreatic inflammation and prevent disease progression
Pre-Clinical Phase 1 Phase 2 Phase 3
Fc-SPINK1
Genetic Pancreatitis

Get in Touch

Interested in learning more about Arwin Health or exploring partnership opportunities? We'd love to hear from you.

hello@arwinhealth.com